Yazar "Hashimoto, Kenji" için listeleme
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Benefical Effects of Sigma-1 Agonist Fluvoxamine for Tardive Dyskinesia and Tardive Akathisia in Patients with Schizophrenia: Report of Three Cases
Albayrak, Yakup; Hashimoto, Kenji (Korean Neuropsychiatric Assoc, 2013)Fluvoxamine is a selective serotonin reuptake inhibitor that is approved for psychiatric disorders such as major depressive episodes and obsessive-compulsive disorder. Beside inhibition of serotonin reuptake, fluvoxamine ... -
Clinical implications of fluvoxamine and fluoxetine with sigma-1 receptor chaperone activity in the treatment of neuropsychiatric disorders
Albayrak, Yakup; Hashimoto, Kenji (Nova Science Publishers, Inc., 2015)Selective serotonin reuptake inhibitors (SSRIs) are used as therapeutic drugs for a number of neuropsychiatric diseases throughout the world. Although all SSRIs act by blockading serotonin transporters, leading to elevated ... -
Decreased serum levels of brain-derived neurotrophic factor in schizophrenic patients with deficit syndrome
Akyol, Esra Soydaş; Albayrak, Yakup; Beyazyüz, Murat; Aksoy, Nurkan; Kuloğlu, Murat; Hashimoto, Kenji (Dove Medical Press Ltd, 2015)Background: Brain-derived neurotrophic factor (BDNF) is a well-established neurotrophin that plays a role in the pathophysiology of numerous psychiatric disorders. Many studies have investigated the serum BDNF levels in ... -
Increased serum G72 protein levels in patients with schizophrenia: a potential candidate biomarker
Akyol, Esra Soydaş; Albayrak, Yakup; Aksoy, Nurkan; Şahin, Başak; Beyazyüz, Murat; Kuloğlu, Murat; Hashimoto, Kenji (Cambridge Univ Press, 2017)Objective: The product of the G72 gene is an activator of d-amino acid oxidase and has been suggested to play a role in the pathogenesis of schizophrenia. Increased G72 protein levels may be associated with disturbed ... -
Increased serum levels of apoptosis in deficit syndrome schizophrenia patients: a preliminary study
Beyazyüz, Murat; Kufeciler, Tarkan; Bulut, Leyla; Ünsal, Cüneyt; Albayrak, Yakup; Akyol, Esra Soydaş; Hashimoto, Kenji (Dove Medical Press Ltd, 2016)Background: Schizophrenia is a chronic and debilitating disorder, the etiology of which remains unclear. Apoptosis is a programmed cell death mechanism that might be implicated in neuropsychiatric disorders, including ... -
Reduced serum paraoxonase 1 (PON1) activity in patients with schizophrenia treated with olanzapine but not quetiapine
Ünsal, Cüneyt; Albayrak, Yakup; Albayrak, Neslihan; Kuloğlu, Murat; Hashimoto, Kenji (Dove Medical Press Ltd, 2013)Background: Second generation antipsychotics (SGAs) are currently the most prescribed drugs in the treatment of schizophrenia. Despite their advantages, which include greater improvement in negative symptoms, cognitive ... -
Sigma-1 Receptor Agonists and Their Clinical Implications in Neuropsychiatric Disorders
Albayrak, Yakup; Hashimoto, Kenji (Springer International Publishing Ag, 2017)Accumulating evidence suggests that sigma-1 receptors play a role in the pathophysiology of neuropsychiatric diseases, as well as in the mechanisms of some selective serotonin reuptake inhibitors (SSRIs). Among the SSRIs, ...